Francis Berenbaum Selected Research

tanezumab

1/2022	Response to: 'Use of tanezumab for patients with hip and knee osteoarthritis with reference to a randomised clinical trial by Berenbaum and colleagues' by Riddle and Perera.
1/2022	General Safety and Tolerability of Subcutaneous Tanezumab for Osteoarthritis: A Pooled Analysis of Three Randomized, Placebo-Controlled Trials.
1/2022	WOMAC Meaningful Within-patient Change: Results From 3 Studies of Tanezumab in Patients With Moderate-to-severe Osteoarthritis of the Hip or Knee.
12/2021	Single and Composite Endpoints of Within-Patient Improvement in Symptoms: Pooled Tanezumab Data in Patients with Osteoarthritis.
12/2021	Gender, age, disease severity, body mass index and diabetes may not affect response to subcutaneous tanezumab in patients with osteoarthritis after 16 weeks of treatment. A subgroup analysis of placebo-controlled trials.
1/2021	Subcutaneous tanezumab for osteoarthritis: Is the early improvement in pain and function meaningful and sustained?
1/2020	Subcutaneous tanezumab for osteoarthritis of the hip or knee: efficacy and safety results from a 24-week randomised phase III study with a 24-week follow-up period.

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Francis Berenbaum Research Topics

Disease

59	Osteoarthritis 06/2022 - 09/2004
28	Rheumatoid Arthritis 01/2022 - 02/2002
26	Pain (Aches) 01/2022 - 03/2003
16	Arthritis (Polyarthritis) 01/2022 - 07/2003
15	Inflammation (Inflammations) 02/2022 - 03/2003
15	Knee Osteoarthritis 01/2022 - 09/2012
12	COVID-19 04/2022 - 01/2020
7	Obesity 11/2019 - 12/2008
6	Axial Spondyloarthritis 11/2022 - 11/2014
5	Hip Osteoarthritis (Coxarthrosis) 01/2022 - 01/2020
5	Rheumatic Diseases (Rheumatism) 01/2021 - 05/2011
5	Disease Progression 01/2020 - 01/2013
5	Infections 12/2016 - 01/2006
4	Joint Diseases (Joint Disease) 10/2021 - 03/2007
3	Cardiovascular Diseases (Cardiovascular Disease) 06/2022 - 01/2017
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2021 - 01/2013
3	Metabolic Diseases (Metabolic Disease) 01/2021 - 01/2016
3	Hypertension (High Blood Pressure) 01/2021 - 01/2008
3	Necrosis 01/2021 - 01/2006
3	Synovitis 01/2019 - 11/2010
3	Back Pain (Backache) 01/2018 - 01/2015
2	Bursitis (Adhesive Capsulitis) 01/2022 - 01/2021
2	Musculoskeletal Diseases (Musculoskeletal Disease) 01/2021 - 01/2021
2	Sacroiliitis 01/2021 - 01/2018
2	Vitamin D Deficiency 11/2020 - 12/2016
2	Insulin Resistance 01/2019 - 01/2013
2	Injection Site Reaction 01/2019 - 01/2019
2	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 01/2016
2	Type 2 Diabetes Mellitus (MODY) 01/2017 - 02/2013
2	HIV Infections (HIV Infection) 12/2016 - 03/2007
2	Psoriatic Arthritis 11/2016 - 03/2007
2	Spondylarthropathies 11/2016 - 01/2006
2	Fatigue 10/2015 - 01/2012

Drug/Important Bio-Agent (IBA)

13	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2013
8	Pharmaceutical PreparationsIBA 01/2022 - 01/2007
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2015 - 07/2003
7	tanezumabIBA 01/2022 - 01/2020
7	4-hexyloxyaniline (HOA)IBA 10/2021 - 01/2012
7	Hyaluronic Acid (Hyaluronan)IBA 07/2021 - 09/2012
7	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2021 - 03/2002
7	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 07/2021 - 04/2005
7	Interleukin-1 (Interleukin 1)IBA 01/2019 - 10/2004
7	Biological ProductsIBA 01/2019 - 12/2013
6	Methotrexate (Mexate)FDA LinkGeneric 01/2022 - 07/2003
6	Antirheumatic Agents (DMARD)IBA 01/2021 - 10/2007
6	EnzymesIBA 11/2019 - 09/2004
6	AdipokinesIBA 01/2014 - 12/2008
6	Nicotinamide PhosphoribosyltransferaseIBA 01/2014 - 05/2008
5	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2021 - 01/2020
5	InterleukinsIBA 11/2019 - 01/2006
5	CytokinesIBA 01/2018 - 10/2004
4	Cholinergic Agents (Cholinergics)IBA 01/2022 - 01/2016
4	Infliximab (Remicade)FDA Link 01/2021 - 07/2003
4	Analgesics (Analgesic Drugs)IBA 01/2021 - 09/2017
4	AdiponectinIBA 01/2019 - 12/2008
4	C-Reactive ProteinIBA 01/2018 - 12/2012
4	Matrix Metalloproteinases (MMPs)IBA 05/2014 - 01/2006
4	SteroidsIBA 10/2013 - 01/2006
3	COVID-19 VaccinesIBA 04/2022 - 01/2021
3	VaccinesIBA 04/2022 - 01/2021
3	Etanercept (Enbrel)FDA Link 01/2022 - 07/2003
3	Prostaglandins AIBA 01/2022 - 01/2020
3	Vitamin D FDA LinkGeneric 11/2020 - 07/2014
3	Nerve Growth Factor (NGF)IBA 01/2020 - 01/2014
3	AutoantibodiesIBA 01/2020 - 01/2013
3	LeptinIBA 01/2019 - 12/2008
3	tocilizumab (atlizumab)FDA Link 01/2019 - 07/2011
3	Certolizumab Pegol FDA Link 01/2018 - 05/2011
3	ProstaglandinsIBA 01/2006 - 09/2004
3	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 04/2005 - 02/2002
2	salicylhydroxamic acid (SHAM)IBA 02/2022 - 01/2022
2	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2022 - 01/2021
2	GlucocorticoidsIBA 01/2022 - 01/2021
2	Naproxen (Naprosyn)FDA LinkGeneric 04/2021 - 04/2005
2	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2021 - 01/2020
2	Vitamin K FDA Link 01/2021 - 10/2007
2	Opioid Analgesics (Opioids)IBA 12/2020 - 01/2019
2	Acetaminophen (Paracetamol)FDA LinkGeneric 12/2020 - 01/2008
2	ametantrone (HAQ)IBA 11/2020 - 10/2013
2	Abatacept (Orencia)FDA Link 01/2019 - 12/2016
2	lutikizumabIBA 01/2019 - 01/2019
2	FX006IBA 04/2018 - 01/2018
2	Adenosine Diphosphate (ADP)IBA 04/2018 - 01/2018
2	Triamcinolone Acetonide (Azmacort)FDA LinkGeneric 04/2018 - 01/2018
2	Saline SolutionIBA 04/2018 - 01/2017
2	Interleukin-6 (Interleukin 6)IBA 06/2017 - 07/2011
2	Dinoprostone (PGE2)FDA Link 06/2017 - 05/2008
2	Interleukin-8 (Interleukin 8)IBA 06/2017 - 12/2012
2	Phosphorus (Red Phosphorus)IBA 12/2016 - 07/2014
2	Proteins (Proteins, Gene)FDA Link 11/2016 - 09/2004
2	Celecoxib (Celebrex)FDA Link 01/2016 - 04/2005
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 07/2015 - 01/2013

Therapy/Procedure

24	Therapeutics 06/2022 - 03/2002
5	Intra-Articular Injections 04/2018 - 10/2015
3	Vagus Nerve Stimulation 02/2022 - 01/2021
3	Injections 07/2021 - 07/2015
3	Biological Therapy 11/2014 - 11/2004
2	Replacement Arthroplasty 01/2021 - 06/2013
2	Off-Label Use 12/2020 - 01/2020
2	Microspheres (Microsphere) 04/2018 - 01/2018